Description

2-Fluoro-3-(Trifluoromethoxy)Phenol is a high-purity fluorinated phenolic compound, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique structure, featuring both fluorine and a trifluoromethoxy substituent, makes it an essential building block for introducing specific physicochemical properties into target molecules. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and pesticides, where the fluorine and trifluoromethoxy groups enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated compounds for electronic display applications.
• Polymer Chemistry: Acts as a monomer or modifier for creating specialty polymers with enhanced thermal, chemical, or surface properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, etherifications, and other transformations to construct complex molecular architectures in academic and industrial research.

Basic Information

Product Name	2-Fluoro-3-(Trifluoromethoxy)Phenol
CAS No.	1334164-87-2
Molecular Formula	C7H4F4O2
Molecular Weight	196.10 g/mol
Synonyms	2-Fluoro-3-(trifluoromethoxy)phenol; 3-Trifluoromethoxy-2-fluorophenol; 2-Fluoro-α,α,α-trifluoro-3-methoxyphenol; Phenol, 2-fluoro-3-(trifluoromethoxy)-; 2-Fluoro-3-trifluoromethoxyphenol
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-(Trifluoromethoxy)Phenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.