Description

Fmoc-L-Hoser(Otbms)-Oh is a specialized, orthogonally protected amino acid derivative designed for advanced solid-phase peptide synthesis (SPPS). This compound matters for its role in constructing complex peptides and peptidomimetics, particularly where the side chain of the amino acid requires temporary protection to prevent unwanted side reactions during assembly. It is essential for research chemists and process development scientists in the pharmaceutical, biotechnology, and academic research sectors who are developing novel therapeutic peptides, peptide hormones, and diagnostic agents.

Application

• Critical building block in the solid-phase synthesis of complex peptides and peptidomimetics.
• Used in the research and development of novel therapeutic peptides, including antimicrobial peptides (AMPs) and peptide-based drugs.
• Facilitates the synthesis of peptides containing sensitive or reactive amino acid side chains that require orthogonal protection strategies.
• Key intermediate in the production of custom peptides for biochemical assays and structure-activity relationship (SAR) studies.
• Employed in the development of peptide libraries for high-throughput screening in drug discovery.
• Essential for the synthesis of conjugated peptides used in diagnostic imaging and targeted drug delivery systems.

Basic Information

Product Name	Fmoc-L-Hoser(Otbms)-Oh
CAS No.	1333332-17-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Fmoc-Hoser(OtBu)-OH; Fmoc-L-2-Hydroxy-4-(tert-butoxy)-4-oxobutanoic acid; N-(9-Fluorenylmethoxycarbonyl)-L-homoserine tert-butyl ester; Fmoc-Homoserine(OtBu)-OH; Fmoc-L-Homoserine(O-tert-butyl)-OH; Fmoc-Hse(OtBu)-OH; Nα-Fmoc-L-homoserine tert-butyl ester
EINECS	Contact for details

Quality Control

Every batch of Fmoc-L-Hoser(Otbms)-Oh is produced and tested under strict quality management protocols to ensure the high purity and consistency required for sensitive synthetic applications. Our products undergo rigorous quality testing, including advanced chromatographic analysis, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.