Description

5-Pyrimidinecarboxamide, 4-[(2-Methylpropyl)Amino]-n-(Phenylmethyl)-2-[4-[(Tetrahydro-2H-Pyran-3-Yl)Methyl]-1-Piperazinyl]- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents targeting specific biological pathways. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new chemical entities.
• API Synthesis: Serves as a precursor in the multi-step manufacturing of complex, high-value active pharmaceutical ingredients.
• Biochemical Research: Potential use as a tool compound or inhibitor in biochemical assays to study enzyme function and cellular signaling pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	5-Pyrimidinecarboxamide, 4-[(2-Methylpropyl)Amino]-n-(Phenylmethyl)-2-[4-[(Tetrahydro-2H-Pyran-3-Yl)Methyl]-1-Piperazinyl]-
CAS No.	1332708-14-1
Molecular Formula	C26H38N6O2
Molecular Weight	466.62 g/mol
Synonyms	4-(Isobutylamino)-N-benzyl-2-[4-[(tetrahydro-2H-pyran-3-yl)methyl]piperazin-1-yl]pyrimidine-5-carboxamide; N-Benzyl-4-(isobutylamino)-2-[4-[(oxan-3-yl)methyl]piperazin-1-yl]pyrimidine-5-carboxamide; 4-(2-Methylpropylamino)-N-(phenylmethyl)-2-[4-[(tetrahydro-2H-pyran-3-yl)methyl]-1-piperazinyl]-5-pyrimidinecarboxamide; UNII-9K6T5V8T6F; 1332708-14-1; 5-Pyrimidinecarboxamide, 4-[(2-methylpropyl)amino]-N-(phenylmethyl)-2-[4-[(tetrahydro-2H-pyran-3-yl)methyl]-1-piperazinyl]-
EINECS	Contact for details

Quality Control

Our 5-Pyrimidinecarboxamide intermediate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment. Production can be aligned with cGMP guidelines for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.