Description

S-(2,5-Dimethylbenzene)-L-Cysteine is a specialized chiral cysteine derivative where the thiol group is protected by a 2,5-dimethylbenzene moiety. This compound is a crucial building block in pharmaceutical research and development, particularly for the synthesis of peptide-based drugs and enzyme inhibitors. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in advanced organic synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), especially in cysteine protease inhibitor programs.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to introduce protected cysteine residues with enhanced stability.
• Bioconjugation: Serves as a linker or functional handle for site-specific modification of proteins, antibodies, and other biomolecules.
• Chemical Biology Research: Employed in the study of enzyme mechanisms and the design of activity-based probes targeting thiol-dependent enzymes.
• Asymmetric Synthesis: Acts as a chiral auxiliary or ligand precursor in catalytic asymmetric transformations.
• Material Science: Potential use in the synthesis of functionalized polymers and advanced materials with specific surface properties.

Basic Information

Product Name	S-(2,5-Dimethylbenzene)-L-Cysteine
CAS No.	1331895-23-8
Molecular Formula	C11H15NO2S
Molecular Weight	225.31 g/mol
Synonyms	L-Cysteine, S-(2,5-dimethylphenyl)-; (R)-2-Amino-3-((2,5-dimethylphenyl)thio)propanoic acid; S-(2,5-Xylyl)-L-cysteine; S-(2,5-Dimethylphenyl)cysteine; 2,5-Dimethylbenzenethiol, cysteine adduct; Protected L-Cysteine derivative; Chiral cysteine thioether
EINECS	Contact for details

Quality Control

Our S-(2,5-Dimethylbenzene)-L-Cysteine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.