Description

Quinazoline, 2-Iodo- is a halogenated quinazoline derivative, a versatile and valuable building block in advanced organic synthesis. This compound is particularly significant for its role in the development of novel pharmaceutical intermediates and functional materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other biologically active quinazoline-based molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that incorporate the quinazoline scaffold.
• Material Science: Serves as a building block for creating organic semiconductors, ligands for metal-organic frameworks (MOFs), and other functional organic materials.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to introduce the quinazoline moiety into more complex systems.
• Chemical Biology & Proteomics: Can be used to develop molecular probes and tags for studying biological processes and protein interactions.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO laboratory settings.

Basic Information

Product Name	Quinazoline, 2-Iodo-
CAS No.	1331850-55-5
Molecular Formula	C8H5IN2
Molecular Weight	256.04 g/mol
Synonyms	2-Iodoquinazoline; Iodoquinazoline; Quinazoline, iodo-; 2-Iodo-quinazoline; Quinazoline, 2-iodo-; 1331850-55-5; 2IQ
EINECS	Contact for details

Quality Control

Our Quinazoline, 2-Iodo- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.