Description

7-Cyclopentyl-N,n-Dimethyl-2-[[5-[(1R,6S)-9-Methyl-4-Oxo-3,9-Diazabicyclo[4.2.1]Non-3-Yl]-2-Pyridinyl]Amino]-7H-Pyrrolo[2,3-D]Pyrimidine-6-Carboxamide is a sophisticated, high-purity organic compound designed for advanced research and development. This molecule is of significant interest as a key intermediate or active pharmaceutical ingredient (API) in the discovery of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on oncology, kinase inhibition, and other targeted therapeutic areas.

Application

• Pharmaceutical Research & Development: Serves as a critical building block or lead compound in the synthesis of novel drug candidates, particularly for targeted cancer therapies.
• Kinase Inhibitor Development: Used in biochemical assays and screening programs aimed at discovering and optimizing new kinase inhibitors due to its complex heterocyclic structure.
• Preclinical Studies: Employed in in-vitro and in-vivo studies to evaluate pharmacokinetic properties, efficacy, and mechanism of action of potential new drugs.
• Chemical Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Process Chemistry & Scale-Up: Used as an intermediate in the development and optimization of scalable synthetic routes for complex active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for fundamental studies in medicinal chemistry and organic synthesis methodologies.

Basic Information

Product Name	7-Cyclopentyl-N,n-Dimethyl-2-[[5-[(1R,6S)-9-Methyl-4-Oxo-3,9-Diazabicyclo[4.2.1]Non-3-Yl]-2-Pyridinyl]Amino]-7H-Pyrrolo[2,3-D]Pyrimidine-6-Carboxamide
CAS No.	1331846-26-4
Molecular Formula	C28H35N9O2
Molecular Weight	505.64 g/mol
Synonyms	7-Cyclopentyl-N,N-dimethyl-2-({5-[(1R,6S)-9-methyl-4-oxo-3,9-diazabicyclo[4.2.1]non-3-yl]pyridin-2-yl}amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide; (1R,6S)-N2-(6-(Cyclopentylcarbamoyl)-2-(dimethylamino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-9-methyl-3,9-diazabicyclo[4.2.1]nonane-4-carboxamide; BMS-911543 (developmental code); JNJ-911543; Kinase Inhibitor 1331846-26-4; Pyrrolopyrimidine carboxamide derivative
EINECS	Contact for details

Quality Control

Our 7-Cyclopentyl-N,n-Dimethyl-2-[[5-[(1R,6S)-9-Methyl-4-Oxo-3,9-Diazabicyclo[4.2.1]Non-3-Yl]-2-Pyridinyl]Amino]-7H-Pyrrolo[2,3-D]Pyrimidine-6-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.