Description

(2S)-5-[(Z)-N',N''-Dimethylcarbamimidamido]-2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)Pentanoic Acid Hydrochloride is a high-purity, protected amino acid derivative essential for advanced peptide synthesis. This compound serves as a critical Fmoc-protected building block, enabling the precise construction of complex peptide sequences under standard solid-phase conditions. It is primarily required by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, peptidomimetics, and biochemical probes. The CAS number for this compound is 1330286-46-8.

Application

• Solid-Phase Peptide Synthesis (SPPS): As an Fmoc-protected arginine analog for the automated synthesis of custom peptides.
• Pharmaceutical R&D: A key intermediate in the research and development of peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Bioconjugation: For creating peptide-protein or peptide-small molecule conjugates used in targeted drug delivery and diagnostics.
• Chemical Biology: Synthesis of labeled or modified peptides for studying protein-protein interactions and enzyme mechanisms.
• Library Synthesis: Building block for generating combinatorial peptide libraries for high-throughput screening.
• Agrochemical Research: Potential use in developing novel bioactive peptides for crop protection.

Basic Information

Product Name	(2S)-5-[(Z)-N',N''-Dimethylcarbamimidamido]-2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)Pentanoic Acid Hydrochloride
CAS No.	1330286-46-8
Molecular Formula	C24H29N5O4 • HCl
Molecular Weight	488.0 g/mol (approx.)
Synonyms	Fmoc-Arg(Pbf)-OH • HCl; Fmoc-NG,NG'-bis(tert-butoxycarbonyl)-L-arginine hydrochloride; Nα-Fmoc-Nω-Pbf-L-arginine hydrochloride; Fmoc-L-Arg(Pbf)-OH • HCl; Fmoc-Arg(Pbf)-OH hydrochloride; (2S)-2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-5-[(Z)-(N',N''-dimethylcarbamimidamido)]pentanoic acid hydrochloride; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-Nω-[2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl]-L-arginine hydrochloride
EINECS	Contact for details

Quality Control

Our (2S)-5-[(Z)-N',N''-Dimethylcarbamimidamido]-2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)Pentanoic Acid Hydrochloride is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and peptide synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.