Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-8-Ethoxy-6-Fluoro-1,4-Dihydro-7-[(4Ar,7Ar)-Octahydro-6H-Pyrrolo[3,4-B]Pyridin-6-Yl]-4-Oxo-, Rel- CAS NO 1329746-91-9 is a high-purity, complex heterocyclic compound belonging to the fluoroquinolone carboxylic acid class, serving as a critical pharmaceutical intermediate or active pharmaceutical ingredient (API) building block. Its sophisticated molecular architecture is designed to impart potent biological activity, making it essential for advanced therapeutic research and development. This compound is primarily targeted at pharmaceutical manufacturers and contract research organizations (CROs) engaged in the synthesis of novel antibacterial agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the production of next-generation fluoroquinolone antibiotics.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural moiety for creating new antibacterial compounds with enhanced efficacy and spectrum.
• Biomedical Research: Used in biochemical and microbiological assays to study bacterial DNA gyrase and topoisomerase IV inhibition mechanisms.
• Process Chemistry & Scale-Up: Employed in route scouting, optimization, and pilot-scale manufacturing for new drug candidates.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and regulatory submissions in pharmaceutical development.
• Antimicrobial Agent Research: Investigated for potential activity against drug-resistant bacterial strains in academic and industrial R&D settings.

Basic Information

Item	Details
Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-8-Ethoxy-6-Fluoro-1,4-Dihydro-7-[(4Ar,7Ar)-Octahydro-6H-Pyrrolo[3,4-B]Pyridin-6-Yl]-4-Oxo-, Rel-
CAS No.	1329746-91-9
Molecular Formula	C22H26FN3O4
Molecular Weight	415.46 g/mol
Synonyms	Rel-1-Cyclopropyl-8-ethoxy-6-fluoro-1,4-dihydro-7-[(4aR,7aR)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic acid; (Rel)-1-Cyclopropyl-8-ethoxy-6-fluoro-1,4-dihydro-7-[(4aR,7aR)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic acid; 1-Cyclopropyl-8-ethoxy-6-fluoro-1,4-dihydro-7-[(4aR,7aR)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic acid (rel); CAS 1329746-91-9; Fluoroquinolone intermediate; Octahydropyrrolopyridine quinoline derivative.
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid derivative is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing purity, identity, and impurity profiles. Quality is assured through advanced analytical techniques including HPLC, NMR, and MS, meeting the stringent requirements for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.