Description

4-Chloro-3-Ethoxy-2-Fluoroaniline, 97% is a high-purity, multi-substituted aniline derivative that serves as a critical building block in advanced organic synthesis. Its unique halogen and alkoxy substitution pattern makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine and chlorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced functional materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), due to its aromatic core and substituents.
• Dye & Pigment Manufacturing: Employed in the synthesis of specialized azo dyes and high-performance pigments, where the aniline moiety is essential for color development.
• Cross-Coupling Reactions: An effective substrate in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) for creating complex biaryl and aryl amine structures.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D focused on exploring new chemical spaces and reaction methodologies.

Basic Information

Product Name	4-Chloro-3-Ethoxy-2-Fluoroaniline, 97%
CAS No.	1323966-31-9
Molecular Formula	C8H9ClFNO
Molecular Weight	189.61 g/mol
Synonyms	2-Fluoro-4-chloro-3-ethoxyaniline; 3-Ethoxy-2-fluoro-4-chloroaniline; 4-Chloro-3-ethoxy-2-fluorobenzenamine; 1-Amino-4-chloro-3-ethoxy-2-fluorobenzene; Benzenamine, 4-chloro-3-ethoxy-2-fluoro-; 2-Fluoro-4-chloro-3-ethoxybenzenamine
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Ethoxy-2-Fluoroaniline, 97% is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency meet the specified standards. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.