Description

2-Fluoro-5-Methyl-4-(Trifluoromethyl)Benzyl Bromide, 97% is a high-purity, multi-functional benzyl bromide derivative serving as a critical building block in advanced organic synthesis. Its value lies in the strategic combination of fluorine and bromine substituents, which enables precise molecular modifications essential for developing novel compounds with tailored properties. This intermediate is particularly vital for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is used to create active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting CNS disorders, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl and fluorine groups enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to improved electronic properties and device performance.
• Cross-Coupling Reactions: The benzyl bromide moiety acts as an effective electrophile in various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) for constructing complex biaryl systems.
• Functional Polymer Modification: Employed to introduce fluorinated benzyl groups into polymer chains, altering surface properties, chemical resistance, and thermal stability of specialty polymers.
• Chemical Research & Development: An essential reagent in medicinal chemistry and material science R&D for exploring new chemical spaces and structure-activity relationships (SAR).

Basic Information

Item	Details
Product Name	2-Fluoro-5-Methyl-4-(Trifluoromethyl)Benzyl Bromide, 97%
CAS No.	1323966-23-9
Molecular Formula	C10H7BrF4
Molecular Weight	283.06 g/mol
Synonyms	1-(Bromomethyl)-2-fluoro-5-methyl-4-(trifluoromethyl)benzene; 2-Fluoro-α-(bromomethyl)-5-methyl-α,α,α-trifluoro-p-xylene; 4-(Bromomethyl)-2-fluoro-1-methyl-5-(trifluoromethyl)benzene; (2-Fluoro-5-methyl-4-(trifluoromethyl)phenyl)methyl bromide; 2-Fluoro-5-methyl-4-trifluoromethylbenzyl bromide
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Methyl-4-(Trifluoromethyl)Benzyl Bromide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure the 97% minimum purity and identity are met. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled with appropriate precautions for strong acid/organic solvent compatibility. Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.