Description

n-T-Boc-Biocytinamidoethyl Methanethiosulfonate CAS NO 1322623-64-2 is a specialized, high-purity chemical reagent designed for advanced bioconjugation and protein labeling applications. This compound is critical for researchers and manufacturers requiring precise, site-specific modification of biomolecules, particularly in the development of diagnostic assays and targeted therapeutics. It is an essential tool for biochemists, pharmaceutical R&D teams, and diagnostic kit manufacturers working in proteomics, antibody-drug conjugate (ADC) development, and advanced life science research.

Application

• Site-Specific Protein Labeling: Used for the controlled, covalent attachment of biotin or other tags to cysteine residues in proteins and antibodies.
• Antibody-Drug Conjugate (ADC) Linker Chemistry: Serves as a key intermediate or functional linker in the synthesis of targeted cancer therapeutics.
• Diagnostic Assay Development: Enables the biotinylation of capture antibodies or antigens for use in ELISA, lateral flow assays, and other immunoassay platforms.
• Proteomics and Protein Interaction Studies: Facilitates the labeling and subsequent isolation/purification of proteins for mass spectrometry and pull-down assays.
• Surface Functionalization: Used to modify sensor chips, nanoparticles, or other solid supports with biotin for streptavidin-based capture systems.
• Chemical Biology Tool Development: Acts as a critical reagent in the synthesis of novel probes for studying enzyme activity and cellular processes.

Basic Information

Product Name	n-T-Boc-Biocytinamidoethyl Methanethiosulfonate
CAS No.	1322623-64-2
Molecular Formula	C23H42N4O7S2
Molecular Weight	550.73 g/mol
Synonyms	Boc-Biocytinamidoethyl MTS; N-α-(tert-Butoxycarbonyl)-N-ε-biotinyl-L-lysine N-hydroxysuccinimide ester methanethiosulfonate derivative; Biotin-PEG2-MTS; Biotinamidoethyl Methanethiosulfonate, Boc-protected; (2-{2-[2-(5-{2-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamido}pentanamido)ethoxy]ethoxy}ethyl) methanesulfonothioate; Biotinylation Reagent MTS; Protein Labeling Reagent 1322623-64-2
EINECS	Contact for details

Quality Control

Our n-T-Boc-Biocytinamidoethyl Methanethiosulfonate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive research and production applications. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.