Description

N,N'-Bis-(4-Fluoro-Benzyl)-Cyclohexane-1,2-Diamine is a high-purity, chiral diamine derivative featuring fluorinated benzyl groups, offering unique steric and electronic properties for advanced synthesis. This compound is critical for the development of sophisticated ligands and catalysts, particularly in asymmetric synthesis and pharmaceutical intermediate manufacturing. It is primarily sought after by research institutions and industrial chemists in the pharmaceutical, agrochemical, and specialty chemical sectors for creating novel active compounds and materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and antiviral drugs.
• Asymmetric Catalyst/Ligand Precursor: Used to develop novel chiral ligands for transition metal catalysis, enabling enantioselective C-C and C-N bond-forming reactions.
• Agrochemical Research: Employed in the research and development of new-generation herbicides and fungicides with enhanced efficacy and selectivity.
• Material Science: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers, resins, and advanced functional materials.
• Organic Synthesis Reagent: Utilized in academic and industrial R&D for constructing complex molecular architectures requiring a rigid, fluorinated diamine scaffold.

Basic Information

Product Name	N,N'-Bis-(4-Fluoro-Benzyl)-Cyclohexane-1,2-Diamine
CAS No.	1318762-87-6
Molecular Formula	C₂₆H₂₈F₂N₂
Molecular Weight	406.51 g/mol
Synonyms	1,2-Cyclohexanediamine, N1,N2-bis[(4-fluorophenyl)methyl]-; (1R,2R)-N1,N2-Bis(4-fluorobenzyl)cyclohexane-1,2-diamine; (1S,2S)-N1,N2-Bis(4-fluorobenzyl)cyclohexane-1,2-diamine; N,N'-Di(4-fluorobenzyl)cyclohexane-1,2-diamine; 1,2-Bis[(4-fluorobenzyl)amino]cyclohexane; (R,R)- and (S,S)- enantiomers; 4-Fluoro-Benzyl substituted cyclohexanediamine
EINECS	Contact for details

Quality Control

Our N,N'-Bis-(4-Fluoro-Benzyl)-Cyclohexane-1,2-Diamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity determination, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral excess, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (for enantiomerically pure grades)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.