Description

7-Vinylthieno[3,2-D]Pyrimidin-4-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel, targeted therapeutic agents. It is primarily required by research institutions and pharmaceutical companies engaged in the development of small molecule drugs, particularly in oncology and other disease areas where kinase inhibition is a key mechanism of action.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of investigational new drugs (INDs) and active pharmaceutical ingredients (APIs).
• Kinase Inhibitor Development: Used in medicinal chemistry research for the design and construction of novel kinase inhibitor candidates, leveraging its pyrimidine-thiophene core.
• Chemical Biology Research: Employed as a molecular probe or scaffold in biochemical assays to study protein-ligand interactions and signaling pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specialized heterocyclic chemistry.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis methodology and heterocyclic compound properties.

Basic Information

Product Name	7-Vinylthieno[3,2-D]Pyrimidin-4-Amine
CAS No.	1318132-91-0
Molecular Formula	C9H7N3S
Molecular Weight	189.24 g/mol
Synonyms	7-Ethenylthieno[3,2-d]pyrimidin-4-amine; 4-Amino-7-vinylthieno[3,2-d]pyrimidine; Thieno[3,2-d]pyrimidin-4-amine, 7-vinyl-; 1318132-91-0; 7-Vinyl-thieno[3,2-d]pyrimidin-4-ylamine; 7-Vinyl-4-aminothieno[3,2-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 7-Vinylthieno[3,2-D]Pyrimidin-4-Amine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with client specifications and industry best practices for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). For long-term storage, consider using inert atmosphere packaging.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.