Description

3-((6-((5-Chloropyridin-2-Yl)Amino)Pyrimidin-4-Yl)Amino)-4-(Ethylsulfonyl)-n-Methylbenzenesulfonamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of targeted therapeutic agents. Its complex heterocyclic structure makes it a critical building block for research and development in medicinal chemistry. This compound is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing novel kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry R&D: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Research: Used as a reference standard or tool compound in enzymatic assays and target validation studies.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to create complex molecules with specific biological activity.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	3-((6-((5-Chloropyridin-2-Yl)Amino)Pyrimidin-4-Yl)Amino)-4-(Ethylsulfonyl)-n-Methylbenzenesulfonamide
CAS No.	1316059-00-3
Molecular Formula	C19H20ClN7O4S2
Molecular Weight	501.99 g/mol
Synonyms	N-Methyl-3-((6-((5-chloropyridin-2-yl)amino)pyrimidin-4-yl)amino)-4-(ethylsulfonyl)benzenesulfonamide; 3-[(6-{[(5-Chloropyridin-2-yl)amino]pyrimidin-4-yl)amino]-4-(ethylsulfonyl)-N-methylbenzenesulfonamide; 1316059-00-3; 4-(Ethylsulfonyl)-N-methyl-3-({6-[(5-chloro-2-pyridinyl)amino]-4-pyrimidinyl}amino)benzenesulfonamide; Benzenesulfonamide, 3-((6-((5-chloro-2-pyridinyl)amino)-4-pyrimidinyl)amino)-4-(ethylsulfonyl)-N-methyl-; Kinase Inhibitor Intermediate
EINECS	Contact for details

Quality Control

Our 3-((6-((5-Chloropyridin-2-Yl)Amino)Pyrimidin-4-Yl)Amino)-4-(Ethylsulfonyl)-n-Methylbenzenesulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.