Description

5-(1H-Pyrazol-1-Yl)-2-Thioxo-2,3-Dihydropyrimidin-4(1H)-One is a high-purity, heterocyclic organic compound featuring a fused pyrimidine-pyrazole-thione core structure. This specialized intermediate is critical for advanced research and development in medicinal chemistry, offering a versatile scaffold for constructing novel molecular architectures. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers focused on developing new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive heterocyclic framework.
• Material Science Precursor: Acts as a precursor for synthesizing specialized ligands and functional molecules used in catalysis and advanced materials.
• Biochemical Tool Compound: Employed in academic and industrial research as a probe or reference standard for studying biological pathways and enzyme interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise molecular scaffold.

Basic Information

Item	Details
Product Name	5-(1H-Pyrazol-1-Yl)-2-Thioxo-2,3-Dihydropyrimidin-4(1H)-One
CAS No.	1314965-49-5
Molecular Formula	C7H6N4OS
Molecular Weight	194.21 g/mol
Synonyms	4(1H)-Pyrimidinone, 5-(1H-pyrazol-1-yl)-2,3-dihydro-2-thioxo-; 5-(1H-Pyrazol-1-yl)-2-mercapto-4-hydroxypyrimidine; 5-(Pyrazol-1-yl)-2-thioxo-1,2-dihydropyrimidin-4-one; 2-Thioxo-5-(1H-pyrazol-1-yl)-2,3-dihydro-4(1H)-pyrimidinone; 5-(1H-Pyrazol-1-yl)-2-thioxo-1,2,3,4-tetrahydropyrimidin-4-one
EINECS	Contact for details

Quality Control

Our production of 5-(1H-Pyrazol-1-Yl)-2-Thioxo-2,3-Dihydropyrimidin-4(1H)-One adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support development and commercial projects with material produced under a robust quality management system, and specifications can be aligned with cGMP guidelines as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.