Description

2-Chloro-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine hydrochloride is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile and critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of kinase inhibitors and other small molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used as a core scaffold for developing new active ingredients with herbicidal or insecticidal properties.
• Chemical Biology: Serves as a valuable probe or linker in the design of chemical tools for studying biological processes and target engagement.
• Material Science: Potential precursor for the development of novel organic electronic materials or metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for methodological development and exploratory synthesis of novel heterocyclic compounds.

Basic Information

Product Name	2-Chloro-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine hydrochloride
CAS No.	1314790-85-6
Molecular Formula	C7H7ClN3•HCl
Molecular Weight	206.06 g/mol (Free base: 169.60 g/mol)
Synonyms	2-Chloro-5,7-dihydropyrrolo[3,4-d]pyrimidine hydrochloride; 2-Chloro-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine HCl; 2-Chloropyrrolo[3,4-d]pyrimidine hydrochloride; Pyrrolo[3,4-d]pyrimidine, 2-chloro-6,7-dihydro-5H-, hydrochloride; 1314790-85-6 (CAS); 2-Chloro-5H-pyrrolo[3,4-d]pyrimidine hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Chloro-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.