Description

2-(5-Bromo-2-Fluorophenyl)Propan-2-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its bromo-fluorophenyl and tertiary amine structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers requiring a reliable, high-quality building block for complex organic synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for neurological and oncological targets.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its halogenated aromatic structure.
• Material Science: Serves as a precursor for specialty polymers and liquid crystals due to its rigid aromatic core and functional amine group.
• Academic & Contract Research: Employed in university and CRO laboratories for medicinal chemistry programs and structure-activity relationship (SAR) studies.
• Chemical Synthesis: Acts as a versatile starting material for further functionalization, including Buchwald-Hartwig amination or Suzuki coupling reactions.

Basic Information

Product Name	2-(5-Bromo-2-Fluorophenyl)Propan-2-Amine
CAS No.	1314735-57-3
Molecular Formula	C9H11BrFN
Molecular Weight	232.09 g/mol
Synonyms	2-(5-Bromo-2-fluorophenyl)propan-2-amine; 2-Amino-2-(5-bromo-2-fluorophenyl)propane; 1-(5-Bromo-2-fluorophenyl)-1-methylethylamine; 5-Bromo-2-fluoro-α,α-dimethylbenzylamine; α-(5-Bromo-2-fluorophenyl)isopropylamine; 2-(5-Bromo-2-fluorophenyl)-2-propylamine
EINECS	Contact for details

Quality Control

Our 2-(5-Bromo-2-Fluorophenyl)Propan-2-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids and oxidizing agents. This material is moisture-sensitive (hygroscopic); ensure containers are sealed tightly after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.