Description

2-Chloro-5,6,7,8-Tetrahydro-Pyrido[4,3-D]Pyrimidine Hydrochloride is a high-purity heterocyclic building block and pharmaceutical intermediate. This compound is critical for medicinal chemistry research and the development of novel therapeutic agents, particularly in kinase inhibitor programs. It is primarily sought by research institutions and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of kinase inhibitors and other small-molecule drugs.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Chemical Synthesis: Acts as a specialized building block for constructing complex polycyclic nitrogen-containing heterocycles.
• Biochemical Research: Employed in the study of enzyme inhibition mechanisms and biological pathway modulation.
• Process Chemistry: Utilized in route scouting and scale-up synthesis for Active Pharmaceutical Ingredient (API) manufacturing.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global drug development pipelines.

Basic Information

Product Name	2-Chloro-5,6,7,8-Tetrahydro-Pyrido[4,3-D]Pyrimidine Hydrochloride
CAS No.	1314723-39-1
Molecular Formula	C9H11ClN3•HCl
Molecular Weight	234.11 g/mol
Synonyms	2-Chloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine hydrochloride; 2-Chloro-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidine HCl; 2-Chloro-5,6,7,8-tetrahydro-4H-pyrido[4,3-d]pyrimidine hydrochloride; 1314723-39-1; Pyrido[4,3-d]pyrimidine, 2-chloro-5,6,7,8-tetrahydro-, hydrochloride (1:1); 2-Chloro-4H,5H,6H,7H,8H-pyrido[4,3-d]pyrimidine hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Chloro-5,6,7,8-Tetrahydro-Pyrido[4,3-D]Pyrimidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.