Description

1-(2,6-Difluorophenyl)Cyclopropanamine is a high-purity, advanced pharmaceutical intermediate featuring a cyclopropylamine moiety attached to a difluorinated aromatic ring. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring specific molecular geometry and fluorine substitution. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug molecules, especially in central nervous system (CNS) and anti-infective therapeutic categories.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the difluorophenyl group contributes to biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with unique electronic properties.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	1-(2,6-Difluorophenyl)Cyclopropanamine
CAS No.	1314672-24-6
Molecular Formula	C9H9F2N
Molecular Weight	169.17 g/mol
Synonyms	1-(2,6-Difluorophenyl)cyclopropanamine; 2,6-Difluoro-α-(cyclopropylamino)toluene; Cyclopropanamine, 1-(2,6-difluorophenyl)-; 1-(2,6-Difluorophenyl)cyclopropylamine; 2,6-Difluorobenzenecyclopropanamine; (2,6-Difluorophenyl)cyclopropylamine; 1-(2,6-Difluorophenyl)cyclopropaneamine
EINECS	Contact for details

Quality Control

Our 1-(2,6-Difluorophenyl)Cyclopropanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.