Description

Benzenemethanamine, 2-Chloro-α,α-Dimethyl-5-(Trifluoromethyl)- is a specialized aromatic amine derivative featuring a trifluoromethyl group, a key structural motif in modern synthetic chemistry. This compound matters for its role as a versatile and high-value pharmaceutical intermediate and agrochemical building block, enabling the synthesis of molecules with enhanced biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, crop protection, and advanced material sectors.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Serves as a crucial building block for novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl and chloro substituents.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced polymers and functional organic materials with specific electronic properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up.
• Academic and Industrial R&D: Utilized in research laboratories for method development and exploring new chemical entities.

Basic Information

Product Name	Benzenemethanamine, 2-Chloro-α,α-Dimethyl-5-(Trifluoromethyl)-
CAS No.	1314666-26-6
Molecular Formula	C10H11ClF3N
Molecular Weight	237.65 g/mol
Synonyms	2-Chloro-α,α-dimethyl-5-(trifluoromethyl)benzenemethanamine; 1-(2-Chloro-5-(trifluoromethyl)phenyl)-2-methylpropan-2-amine; α-(2-Chloro-5-(trifluoromethyl)phenyl)-tert-butylamine; 2-Chloro-α,α-dimethyl-5-(trifluoromethyl)benzylamine; (2-Chloro-5-(trifluoromethyl)phenyl)(tert-butyl)amine; 1314666-26-6; tert-Butyl(2-chloro-5-(trifluoromethyl)phenyl)amine
EINECS	Contact for details

Quality Control

Our Benzenemethanamine, 2-Chloro-α,α-Dimethyl-5-(Trifluoromethyl)- is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP and ISO compliant manufacturing for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.