Description

(2S)-2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)-3-(3-Phenoxyphenyl)Propanoic Acid CAS NO 1313277-83-6 is a high-purity, non-natural amino acid derivative featuring a fluorenylmethyloxycarbonyl (Fmoc) protecting group and a phenoxyphenyl side chain. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled assembly of complex peptide sequences. It is essential for researchers and manufacturers in pharmaceutical development, particularly for creating novel therapeutic peptides and peptidomimetics.

Application

• Solid-Phase Peptide Synthesis (SPPS): As an Fmoc-protected amino acid, it serves as a key monomer for the sequential construction of custom peptide chains.
• Pharmaceutical Research & Development: Used in the discovery and synthesis of peptide-based drug candidates targeting various diseases.
• Bioconjugation: The reactive carboxylic acid group allows for coupling to other molecules, carriers, or surfaces in bioconjugate chemistry.
• Chemical Biology Probes: Incorporation into peptides used as tools to study protein-protein interactions and biological pathways.
• Process Development: Serves as a starting material or intermediate in the scale-up and optimization of peptide API manufacturing processes.
• Academic Research: Fundamental studies in organic synthesis, peptide chemistry, and material science.

Basic Information

Product Name	(2S)-2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)-3-(3-Phenoxyphenyl)Propanoic Acid
CAS No.	1313277-83-6
Molecular Formula	C30H25NO5
Molecular Weight	479.52 g/mol
Synonyms	Fmoc-3-(3-Phenoxyphenyl)-L-alanine; Fmoc-3-(3-phenoxyphenyl)-D-alanine (enantiomer); N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(3-phenoxyphenyl)-L-alanine; N-α-Fmoc-3-(3-phenoxyphenyl)-L-alanine; Fmoc-L-3-(3-phenoxyphenyl)alanine; (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-3-(3-phenoxyphenyl)propanoic acid; Fmoc-3-(3-phenoxyphenyl)Ala-OH; Fmoc-3-Phenoxyphenylalanine
EINECS	Contact for details

Quality Control

Our (2S)-2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)-3-(3-Phenoxyphenyl)Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for peptide synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.