Description

3-(3-Pyrrolidinyl)-L-Alanine is a non-proteinogenic amino acid derivative featuring a pyrrolidine side chain, which is of significant interest in advanced pharmaceutical research and development. This specialized building block is valued for its unique structural motif that can impart specific conformational and binding properties to peptide-based therapeutics. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of novel drug candidates, particularly in areas such as central nervous system (CNS) disorders and metabolic diseases. The compound's chiral purity and defined stereochemistry are critical for ensuring reproducible biological activity in preclinical studies.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of complex peptide-based active pharmaceutical ingredients (APIs).
• Drug Discovery Research: Used as a constrained amino acid analog in medicinal chemistry to explore structure-activity relationships (SAR) and improve metabolic stability.
• Peptide Synthesis: Incorporated into custom peptides for biochemical assays, target validation, and the development of diagnostic tools.
• Neurological Research: Investigated for potential applications in designing ligands for neurotransmitter receptors and transporters.
• Chemical Biology Probes: Utilized to create labeled or modified peptides for studying protein-protein interactions and enzymatic processes.

Basic Information

Product Name	3-(3-Pyrrolidinyl)-L-Alanine
CAS No.	1313183-06-0
Molecular Formula	C7H12N2O2
Molecular Weight	156.18 g/mol
Synonyms	(2S)-2-Amino-3-(pyrrolidin-3-yl)propanoic acid; L-3-(3-Pyrrolidinyl)alanine; 3-Pyrrolidin-3-yl-L-alanine; (S)-2-Amino-3-(pyrrolidin-3-yl)propionic acid; 3-Pyrrolidinylalanine; 3-(3-Pyrrolidyl)-L-alanine; Pyrrolidine-3-yl-L-alanine
EINECS	Contact for details

Quality Control

Our 3-(3-Pyrrolidinyl)-L-Alanine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry guidelines to support our customers' regulatory and documentation needs in pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.