Description

Boc-D-Dab(Ivdde)-Oh is a protected amino acid derivative, specifically a Boc-protected D-2,4-diaminobutyric acid (D-Dab) residue with an isovaleryl side chain. This compound is a critical building block in the solid-phase peptide synthesis (SPPS) of complex peptides and peptidomimetics, offering precise stereochemical control. It is primarily utilized by pharmaceutical R&D departments, biotechnology companies, and academic research laboratories engaged in developing novel therapeutic peptides, antimicrobial agents, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key chiral intermediate for the controlled incorporation of the D-2,4-diaminobutyric acid moiety into peptide chains.
• Pharmaceutical Research: Synthesis of peptide-based drug candidates, including antimicrobial peptides (AMPs), hormone analogs, and targeted therapeutics.
• Peptidomimetic Design: Used to create modified peptides with enhanced stability, bioavailability, or receptor specificity.
• Biochemical Tool Development: Building block for labeled peptides, affinity tags, and substrates used in enzymatic assays and diagnostic research.
• Academic & Contract Research: Essential reagent for synthetic chemistry and medicinal chemistry projects in university and CRO settings.

Basic Information

Product Name	Boc-D-Dab(Ivdde)-Oh
CAS No.	1313054-88-4
Molecular Formula	C₁₆H₂₈N₂O₅
Molecular Weight	328.41 g/mol
Synonyms	Boc-D-Dab(Ivdde)-OH; (R)-2-((tert-Butoxycarbonyl)amino)-4-((3-methylbutanoyl)amino)butanoic acid; Nα-Boc-Nδ-isovaleryl-D-2,4-diaminobutyric acid; Boc-D-Dab(Iv)-OH; Boc-D-Dab(NH-Iv)-OH; D-Boc-Dab(Ivdde)-OH; tert-Butyl (R)-(1-((3-methylbutanamido)methyl)-3-carboxypropyl)carbamate
EINECS	Contact for details

Quality Control

Our Boc-D-Dab(Ivdde)-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and spectroscopic identification (NMR, MS), to ensure it meets the high standards required for advanced peptide synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and specification compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (D-isomer)
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.