Description

(9H-Fluoren-9-Yl)Methoxy]Carbonyl D-Hoarg(Pbf)-Oh is a specialized, high-purity amino acid derivative designed for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring precise control over side-chain protection during the construction of complex peptide sequences. It is primarily utilized by the pharmaceutical, biotechnology, and academic research sectors for the development of novel therapeutic peptides and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key building block for the controlled incorporation of protected arginine analogs into peptide chains.
• Pharmaceutical Research: Used in the research and development of peptide-based drug candidates, including hormones, enzyme inhibitors, and antimicrobial agents.
• Bioconjugation: Facilitates the site-specific modification of peptides for creating targeted drug delivery systems or diagnostic conjugates.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to discover new bioactive peptide leads.
• Process Development: Supports scale-up and optimization of peptide manufacturing processes under current Good Manufacturing Practice (cGMP) guidelines.

Basic Information

Product Name	(9H-Fluoren-9-Yl)Methoxy]Carbonyl D-Hoarg(Pbf)-Oh
CAS No.	1313054-60-2
Molecular Formula	C31H33N5O7S
Molecular Weight	619.69 g/mol
Synonyms	Fmoc-D-Hoarg(Pbf)-OH; Fmoc-NG-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-NG'-hydroxy-D-arginine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-NG-hydroxy-NG'-[(2,2,4,6,7-pentamethyldihydrobenzofuran-5-yl)sulfonyl]-D-arginine; Fmoc-Hoarg(Pbf)-OH; Fmoc-D-NG-hydroxy-NG'-Pbf-arginine
EINECS	Contact for details

Quality Control

Our production of (9H-Fluoren-9-Yl)Methoxy]Carbonyl D-Hoarg(Pbf)-Oh adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive applications. All material is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We operate under a quality management system and can supply material suitable for research and development under current Good Manufacturing Practice (cGMP) guidelines for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity. For long-term storage, consider storing desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.