Description

Fmoc-D-Norarg(Pbf)-Oh] CAS NO 1313054-59-9 is a high-purity, orthogonally protected amino acid derivative specifically engineered for solid-phase peptide synthesis (SPPS). This compound is critical for the controlled incorporation of the D-isomer of norarginine into complex peptide sequences, enabling advanced research in peptide-based drug discovery and development. It is an essential building block for pharmaceutical researchers, medicinal chemists, and biotech companies focused on creating novel therapeutic peptides, peptidomimetics, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key protected amino acid building block for the automated synthesis of complex peptides.
• Pharmaceutical Research: For the development of novel peptide-based therapeutics, including antimicrobial peptides, hormone analogs, and targeted drug delivery systems.
• Medicinal Chemistry: Enabling structure-activity relationship (SAR) studies by introducing the D-norarginine moiety to modulate peptide stability, bioavailability, and receptor binding.
• Bioconjugation: Used in the site-specific modification of peptides and proteins for diagnostic or therapeutic applications.
• Biochemical Probes: Synthesis of labeled or tagged peptides for use in biochemical assays and mechanistic studies.
• Academic Research: A fundamental reagent for university and institutional labs studying peptide chemistry, enzymology, and molecular biology.

Basic Information

Product Name	Fmoc-D-Norarg(Pbf)-Oh] CAS NO 1313054-59-9
CAS No.	1313054-59-9
Molecular Formula	C32H43N5O7S
Molecular Weight	641.79 g/mol
Synonyms	Fmoc-D-Norarg(Pbf)-OH; N-α-Fmoc-N-ω-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-D-norarginine; Fmoc-D-2-amino-5-[(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)amino]pentanoic acid; (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-((2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonamido)pentanoic acid; D-Norarginine(Pbf)-Fmoc; Fmoc-D-Norarginine(Pbf)-OH; Fmoc-D-Norarg(Pbf)-OH; Fmoc-D-homoArg(Pbf)-OH (common alias)
EINECS	Contact for details

Quality Control

Our Fmoc-D-Norarg(Pbf)-Oh] CAS NO 1313054-59-9 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for advanced peptide synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral purity is provided with every shipment to guarantee batch-to-batch consistency and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (D-isomer)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.