Description

2-Amino-D-Tryptophan is a non-natural, enantiomerically pure derivative of the essential amino acid tryptophan, distinguished by an additional amino group on the indole ring. This structural modification makes it a valuable chiral building block and a key intermediate in advanced pharmaceutical synthesis and biochemical research. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents, peptide-based drugs, and as a standard in analytical method development.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of complex drug candidates, particularly in oncology and neurology research.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate modified tryptophan residues, altering peptide stability and bioactivity.
• Biochemical Research: Serves as a precursor or inhibitor in enzymatic studies and metabolic pathway analysis.
• Reference Standard: Employed as a high-purity analytical standard in HPLC, LC-MS, and NMR for quality control and method validation.
• Proteomics & Labeling: Potential use in chemical proteomics for labeling and studying protein-protein interactions.
• Asymmetric Catalysis: Acts as a ligand or catalyst component in asymmetric synthesis due to its chiral centers.

Basic Information

Product Name	2-Amino-D-Tryptophan
CAS No.	1313054-34-0
Molecular Formula	C11H13N3O2
Molecular Weight	219.24 g/mol
Synonyms	D-2-Aminotryptophan; (R)-2-Amino-1H-indole-3-propanoic acid; (R)-2-Aminotryptophan; 2-Amino-D-Trp; 2-NH2-D-Trp; H-2-Amino-D-Trp-OH; 2-Amino-(R)-tryptophan; 2-Azanyl-D-tryptophan
EINECS	Contact for details

Quality Control

Every batch of our 2-Amino-D-Tryptophan is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support with detailed Certificates of Analysis (COA), which include data from chiral HPLC, NMR, and mass spectrometry. Our quality commitment aligns with the standards required for research and cGMP-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (D-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.