Description

Fmoc-Norarg(Pbf)-Oh is a protected amino acid derivative essential for solid-phase peptide synthesis (SPPS). This high-purity building block is critical for researchers and manufacturers requiring precise control over peptide sequence and structure. It is primarily used by pharmaceutical R&D teams, biotechnology companies, and CROs engaged in the development of novel therapeutic peptides, peptide hormones, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected amino acid for the automated, stepwise assembly of complex peptide chains.
• Pharmaceutical Research: For the discovery and development of peptide-based drug candidates targeting various diseases.
• Bioconjugation: Used to introduce specific functional groups or arginine analogs into proteins or other biomolecules.
• Combinatorial Chemistry: Serves as a valuable scaffold in libraries for high-throughput screening of bioactive compounds.
• Biochemical Tool Development: For creating labeled peptides, enzyme substrates, or inhibitors used in proteomics and signal transduction studies.
• Academic Research: Fundamental studies in peptide chemistry, structure-activity relationships (SAR), and molecular biology.

Basic Information

Product Name	Fmoc-Norarg(Pbf)-Oh
CAS No.	1313054-32-8
Molecular Formula	C31H40N4O7S
Molecular Weight	612.74 g/mol
Synonyms	Fmoc-Norarginine(Pbf)-OH; N-α-Fmoc-N-ω-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-norarginine; Fmoc-L-Norarginine(Pbf)-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-ω-[(2,2,4,6,7-pentamethyldihydrobenzofuran-5-yl)sulfonyl]-L-norarginine; Fmoc-Norarg(Pbf)-OH; Fmoc-Norarginine(Pbf)-OH CAS 1313054-32-8; (2S)-5-[[(2,2,4,6,7-Pentamethyldihydrobenzofuran-5-yl)sulfonyl]amino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)pentanoic acid
EINECS	Contact for details

Quality Control

Our Fmoc-Norarg(Pbf)-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive research and production applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.