Description

Boc-D-Dap(Ivdde)-Oh is a protected, non-proteinogenic amino acid derivative, specifically designed for advanced peptide synthesis. This high-purity building block is critical for researchers and manufacturers requiring precise control over peptide structure and stereochemistry. It is primarily utilized in pharmaceutical R&D for the development of novel therapeutic peptides and peptidomimetics, where its specialized protecting groups enable complex, multi-step synthetic strategies.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of the D-diaminopropionic acid (D-Dap) moiety into peptide chains.
• Pharmaceutical Research: Used in the discovery and development of peptide-based drugs, including antimicrobial peptides, hormone analogs, and targeted therapeutics.
• Peptidomimetic Design: Serves as a scaffold for creating stable, bioavailable compounds that mimic natural peptide structures.
• Bioconjugation: The orthogonal protecting groups (Boc and Ivdde) allow for selective deprotection, facilitating site-specific labeling or conjugation with other molecules.
• Chemical Biology Probes: Employed in the synthesis of labeled or modified peptides used to study biological pathways and protein interactions.

Basic Information

Product Name	Boc-D-Dap(Ivdde)-Oh
CAS No.	1313054-31-7
Molecular Formula	C₁₇H₂₉N₃O₆
Molecular Weight	371.43 g/mol
Synonyms	(2R)-3-[[(4-Methyl-2,6,7-trioxabicyclo[2.2.2]octan-1-yl)methoxy]amino]-2-[(tert-butoxycarbonyl)amino]propanoic acid; Boc-D-Dap(Ivdde)-OH; N-α-Boc-N-β-(Ivdde)-D-diaminopropionic acid; tert-Butyl ((R)-3-(((4-methyl-2,6,7-trioxabicyclo[2.2.2]octan-1-yl)methoxy)amino)-1-carboxypropyl)carbamate; Boc-D-Dap(Ivdde); D-Dap(Ivdde)-Boc-OH
EINECS	Contact for details

Quality Control

Every batch of Boc-D-Dap(Ivdde)-Oh is produced under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with standards relevant to pharmaceutical intermediates and fine chemical manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.