Description

7-Bromo-4-Chloro-5H-Pyrrolo[3,2-D]Pyrimidin-2-Amine is a high-purity heterocyclic building block of significant importance in modern pharmaceutical research and development. This compound serves as a critical synthetic intermediate for the construction of novel small molecule therapeutics, particularly kinase inhibitors. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for lead optimization and active pharmaceutical ingredient (API) synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry Building Block: Used for structure-activity relationship (SAR) studies and lead compound optimization in drug discovery programs.
• Biochemical Research: Employed as a tool compound or a core scaffold for developing chemical probes to study biological pathways.
• Agrochemical Development: Serves as an intermediate in the research and synthesis of novel crop protection agents.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process scale-up for client projects.
• Academic Research: Used in university and institutional labs for methodological development and exploring new chemical entities.

Basic Information

Product Name	7-Bromo-4-Chloro-5H-Pyrrolo[3,2-D]Pyrimidin-2-Amine
CAS No.	1311275-31-6
Molecular Formula	C6H4BrClN4
Molecular Weight	247.48 g/mol
Synonyms	7-Bromo-4-chloro-5H-pyrrolo[3,2-d]pyrimidin-2-amine; 2-Amino-7-bromo-4-chloro-5H-pyrrolo[3,2-d]pyrimidine; 4-Chloro-7-bromo-5H-pyrrolo[3,2-d]pyrimidin-2-amine; 1311275-31-6; 7-Bromo-4-chloro-2-amino-5H-pyrrolo[3,2-d]pyrimidine; Pyrrolo[3,2-d]pyrimidin-2-amine, 7-bromo-4-chloro-5H-
EINECS	Contact for details

Quality Control

Our 7-Bromo-4-Chloro-5H-Pyrrolo[3,2-D]Pyrimidin-2-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.