Description

4-Chloro-7-Fluoro-5H-Pyrrolo[3,2-D]Pyrimidine is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters as a critical intermediate in the development of novel pharmaceutical agents, particularly kinase inhibitors and other targeted therapeutics. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce complex molecular scaffolds into their target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small molecule kinase inhibitors for oncology and inflammatory disease research.
• Agrochemical Research: Used as a building block for developing new active ingredients with enhanced efficacy and selectivity.
• Chemical Biology Probes: Serves as a core structure for creating tool compounds to study enzyme function and cellular signaling pathways.
• Material Science: Potential monomer or precursor for specialty polymers and organic electronic materials due to its fused heterocyclic system.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development programs for global clients.
• Academic Research: Utilized in university and institutional labs for methodological development and exploring new chemical space in heterocyclic chemistry.

Basic Information

Product Name	4-Chloro-7-Fluoro-5H-Pyrrolo[3,2-D]Pyrimidine
CAS No.	1311275-30-5
Molecular Formula	C6H3ClFN3
Molecular Weight	171.56 g/mol
Synonyms	4-Chloro-7-fluoro-5H-pyrrolo[3,2-d]pyrimidine; 7-Fluoro-4-chloro-5H-pyrrolo[3,2-d]pyrimidine; 5H-Pyrrolo[3,2-d]pyrimidine, 4-chloro-7-fluoro-; 4-Chloro-7-fluoro-5H-pyrrolo[3,2-d]pyrimidine (CAS 1311275-30-5); 4-Chloro-7-fluoro-5H-pyrrolo[3,2-d]pyrimidine; Pyrrolo[3,2-d]pyrimidine, 4-chloro-7-fluoro-5H-
EINECS	Contact for details

Quality Control

Our 4-Chloro-7-Fluoro-5H-Pyrrolo[3,2-D]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.