Description

(9H-Fluoren-9-Yl)Methoxy]Carbonyl D-Dbu(Boc)-Oh is a specialized, protected amino acid derivative used as a critical building block in solid-phase peptide synthesis (SPPS). This compound matters because it provides the essential D-2,4-diaminobutyric acid (D-Dbu) side chain with orthogonal protection, enabling the precise construction of complex and biologically active peptides. Pharmaceutical researchers and fine chemical manufacturers need this high-purity intermediate for developing therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key monomer for the controlled incorporation of D-2,4-diaminobutyric acid residues into peptide chains.
• Pharmaceutical R&D: Used in the research and development of novel peptide-based therapeutics, including antimicrobial peptides and hormone analogs.
• Bioconjugation: Serves as a linker or modified amino acid for creating peptide-protein or peptide-small molecule conjugates.
• Combinatorial Chemistry: Employed in libraries for drug discovery to explore structure-activity relationships (SAR).
• Biochemical Research: Utilized in the study of peptide structure, function, and receptor interactions.
• Custom Peptide Production: An essential raw material for CROs and CDMOs offering bespoke peptide manufacturing services.

Basic Information

Product Name	(9H-Fluoren-9-Yl)Methoxy]Carbonyl D-Dbu(Boc)-Oh
CAS No.	1310680-44-4
Molecular Formula	C25H30N2O6
Molecular Weight	454.52 g/mol
Synonyms	Fmoc-D-Dbu(Boc)-OH; Nα-Fmoc-Nγ-Boc-D-2,4-diaminobutyric acid; Fmoc-D-Dab(Boc)-OH; (2R)-4-[[(2-Methylpropan-2-yl)oxycarbonyl]amino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)butanoic acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N'-[(1,1-dimethylethoxy)carbonyl]-D-2,4-diaminobutyric acid; D-Dbu(Fmoc,Boc)-OH; Fmoc-D-2,4-diaminobutyric acid(Boc)-OH; Boc-D-Dbu(Fmoc)-OH
EINECS	Contact for details

Quality Control

Our (9H-Fluoren-9-Yl)Methoxy]Carbonyl D-Dbu(Boc)-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure compliance with exacting standards for peptide synthesis. Certificates of Analysis (COA) detailing identity, purity, and specific impurities are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% D-isomer
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.