Description

Ethyl 7-[(E)-2-(Dimethylamino)Vinyl]-2-Pyridin-4-Yl[1,2,4]Triazolo[1,5-A]Pyrimidine-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing new drug candidates, especially within oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of investigational new drugs and targeted therapies.
• API Development: Serves as a core structural component for building novel Active Pharmaceutical Ingredients with potential kinase inhibitory or receptor-modulating activity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery programs.
• Biochemical Research: Employed as a tool compound or a ligand in biochemical assays and proteomics research.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for producing specialized, high-value chemical entities.
• Academic Research: Applied in university and institutional labs for heterocyclic chemistry studies and the development of new synthetic methodologies.

Basic Information

Product Name	Ethyl 7-[(E)-2-(Dimethylamino)Vinyl]-2-Pyridin-4-Yl[1,2,4]Triazolo[1,5-A]Pyrimidine-6-Carboxylate
CAS No.	1306753-67-2
Molecular Formula	C19H20N6O2
Molecular Weight	364.40 g/mol
Synonyms	Ethyl 7-[(E)-2-(dimethylamino)ethenyl]-2-(4-pyridinyl)[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate; 7-[(E)-2-(Dimethylamino)vinyl]-2-(pyridin-4-yl)[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester; [1,2,4]Triazolo[1,5-a]pyrimidine-6-carboxylic acid, 7-[(E)-2-(dimethylamino)ethenyl]-2-(4-pyridinyl)-, ethyl ester; Ethyl 7-(2-(dimethylamino)vinyl)-2-(pyridin-4-yl)[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 7-[(E)-2-(Dimethylamino)Vinyl]-2-Pyridin-4-Yl[1,2,4]Triazolo[1,5-A]Pyrimidine-6-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with exacting standards for pharmaceutical intermediates. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	Yellow to brown solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.