Description

1-{7-[(E)-2-(Dimethylamino)Vinyl][1,2,4]Triazolo-[1,5-A]Pyrimidin-6-Yl}Ethanone is a specialized heterocyclic building block featuring a fused triazolopyrimidine core with a dimethylamino vinyl ketone functional group. This compound matters as a high-value synthetic intermediate, offering a versatile scaffold for constructing complex molecules in advanced research and development. It is primarily needed by pharmaceutical and agrochemical R&D teams for applications in medicinal chemistry, including the synthesis of potential kinase inhibitors and other biologically active compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for targeted therapies.
• Medicinal Chemistry Research: Used as a core scaffold for constructing libraries of compounds for high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new active ingredients for crop protection.
• Chemical Biology Probes: Utilized in the development of molecular probes to study enzyme function and biological pathways.
• Material Science Research: Investigated as a precursor for advanced organic electronic materials due to its conjugated structure.

Basic Information

Product Name	1-{7-[(E)-2-(Dimethylamino)Vinyl][1,2,4]Triazolo-[1,5-A]Pyrimidin-6-Yl}Ethanone
CAS No.	1306753-62-7
Molecular Formula	C₁₁H₁₃N₅O
Molecular Weight	231.25 g/mol
Synonyms	1-[7-[(E)-2-(Dimethylamino)ethenyl][1,2,4]triazolo[1,5-a]pyrimidin-6-yl]ethanone; 6-Acetyl-7-[(E)-2-(dimethylamino)vinyl][1,2,4]triazolo[1,5-a]pyrimidine; (E)-1-(7-(2-(Dimethylamino)vinyl)-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)ethan-1-one; CAS 1306753-62-7; Dimethylamino vinyl triazolopyrimidinyl ethanone
EINECS	Contact for details

Quality Control

Our 1-{7-[(E)-2-(Dimethylamino)Vinyl][1,2,4]Triazolo-[1,5-A]Pyrimidin-6-Yl}Ethanone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP principles ensures reliable supply for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.