Description

1-{7-[(E)-2-(Dimethylamino)Vinyl]-2-Methyl-[1,2,4]Triazolo[1,5-A]Pyrimidin-6-Yl}Ethanone is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused triazolopyrimidine structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in oncology and antiviral research.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates targeting specific enzymes and receptors.
• Organic Synthesis Building Block: Used in research-scale and process chemistry for constructing complex heterocyclic frameworks.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Biochemical Research: Potential use as a tool compound or probe in biochemical assays and mechanism-of-action studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for pioneering synthetic methodology and new compound library generation.

Basic Information

Product Name	1-{7-[(E)-2-(Dimethylamino)Vinyl]-2-Methyl-[1,2,4]Triazolo[1,5-A]Pyrimidin-6-Yl}Ethanone
CAS No.	1306753-60-5
Molecular Formula	C₁₄H₁₇N₅O
Molecular Weight	271.32 g/mol
Synonyms	1-[7-[(E)-2-(Dimethylamino)ethenyl]-2-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl]ethanone; 1-(7-((E)-2-(Dimethylamino)vinyl)-2-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)ethan-1-one; 6-Acetyl-7-[(E)-2-(dimethylamino)vinyl]-2-methyl-[1,2,4]triazolo[1,5-a]pyrimidine; CAS 1306753-60-5; Advanced Triazolopyrimidine Intermediate
EINECS	Contact for details

Quality Control

Our production of 1-{7-[(E)-2-(Dimethylamino)Vinyl]-2-Methyl-[1,2,4]Triazolo[1,5-A]Pyrimidin-6-Yl}Ethanone adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested against rigorous in-house specifications, which are aligned with the standards expected for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed after each use to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.