Description

1-{2-(Benzylthio)-7-[(E)-2-(Dimethylamino)Vinyl]-[1,2,4]Triazolo[1,5-A]Pyrimidin-6-Yl}Ethanone is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing new drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, especially in oncology and central nervous system (CNS) research.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms or protein-ligand interactions.
• Organic Synthesis Building Block: Utilized in academic and industrial research for constructing complex nitrogen-containing heterocycles.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	1-{2-(Benzylthio)-7-[(E)-2-(Dimethylamino)Vinyl]-[1,2,4]Triazolo[1,5-A]Pyrimidin-6-Yl}Ethanone
CAS No.	1306753-48-9
Molecular Formula	C20H21N5OS
Molecular Weight	379.48 g/mol
Synonyms	1-[2-(Benzylsulfanyl)-7-[(E)-2-(dimethylamino)ethenyl]-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl]ethanone; 1-(2-(Benzylthio)-7-((E)-2-(dimethylamino)vinyl)-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)ethan-1-one; CAS 1306753-48-9; Ethanone, 1-[2-(benzylthio)-7-[(E)-2-(dimethylamino)ethenyl]-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl]-; Advanced Triazolopyrimidine Intermediate
EINECS	Contact for details

Quality Control

Our 1-{2-(Benzylthio)-7-[(E)-2-(Dimethylamino)Vinyl]-[1,2,4]Triazolo[1,5-A]Pyrimidin-6-Yl}Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis, to ensure it meets the exacting standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.