Description

5,6-Dimethyl-2-[(4-Phenoxyphenyl)Amino]Pyrimidin-4(3H)-One is a high-purity, advanced pharmaceutical intermediate belonging to the aminopyrimidinone class of heterocyclic compounds. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel, small-molecule therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and development, particularly within oncology and kinase inhibitor research.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of targeted kinase inhibitors and other biologically active molecules.
• Drug Discovery Research: Serves as a core scaffold for medicinal chemistry programs, enabling the exploration of structure-activity relationships (SAR) in new drug candidates.
• Biochemical Tool Compound: Used in vitro to study enzyme inhibition and cellular signaling pathways relevant to disease mechanisms.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for scale-up and cGMP production of active pharmaceutical ingredients (APIs).
• Academic Research: Employed in university and institutional labs for fundamental organic synthesis and pharmacological studies.

Basic Information

Product Name	5,6-Dimethyl-2-[(4-Phenoxyphenyl)Amino]Pyrimidin-4(3H)-One
CAS No.	1306739-91-2
Molecular Formula	C18H17N3O2
Molecular Weight	307.35 g/mol
Synonyms	2-[(4-Phenoxyphenyl)amino]-5,6-dimethyl-4(3H)-pyrimidinone; 5,6-Dimethyl-2-((4-phenoxyphenyl)amino)pyrimidin-4(3H)-one; 4(3H)-Pyrimidinone, 2-[(4-phenoxyphenyl)amino]-5,6-dimethyl-; 1306739-91-2; 2-Amino-5,6-dimethyl-4-(4-phenoxyanilino)pyrimidine
EINECS	Contact for details

Quality Control

Every batch of our 5,6-Dimethyl-2-[(4-Phenoxyphenyl)Amino]Pyrimidin-4(3H)-One is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support regulatory filings. A detailed Certificate of Analysis (COA) documenting purity (typically ≥97% by HPLC), residual solvents, and other critical parameters is available with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.