Description

5-Benzyl-2-[(4-Fluorophenyl)Amino]-6-Methylpyrimidin-4(3H)-One is a high-purity, advanced pharmaceutical intermediate belonging to the pyrimidinone class of heterocyclic compounds. This compound is of significant commercial interest for its role as a critical building block in the research and development of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in drug discovery programs, particularly those targeting kinase inhibition and other therapeutic pathways.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the multi-step synthesis of potential drug candidates, especially kinase inhibitors.
• Drug Discovery Research: Used as a core scaffold or building block in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Biochemical Research: Employed in vitro as a reference standard or tool compound for studying enzymatic activity and biological pathways.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for producing specialized, high-value chemical entities.
• Academic Research: Applied in university and institutional laboratories for investigations into novel organic synthesis methodologies and heterocyclic chemistry.

Basic Information

Product Name	5-Benzyl-2-[(4-Fluorophenyl)Amino]-6-Methylpyrimidin-4(3H)-One
CAS No.	1306739-76-3
Molecular Formula	C18H16FN3O
Molecular Weight	309.34 g/mol
Synonyms	5-Benzyl-2-[(4-fluorophenyl)amino]-6-methyl-4(3H)-pyrimidinone; 2-((4-Fluorophenyl)amino)-5-benzyl-6-methylpyrimidin-4(3H)-one; 4(3H)-Pyrimidinone, 5-benzyl-2-[(4-fluorophenyl)amino]-6-methyl-; 1306739-76-3; 5-Benzyl-2-(4-fluoroanilino)-6-methylpyrimidin-4-ol; 2-(4-Fluoroanilino)-5-benzyl-6-methyl-3,4-dihydropyrimidin-4-one
EINECS	Contact for details

Quality Control

Our production of 5-Benzyl-2-[(4-Fluorophenyl)Amino]-6-Methylpyrimidin-4(3H)-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.