Description

2-Hydroxy-3-Phenyl-4H-Pyrimido[1,2-A]Pyrimidin-4-One is a high-purity, heterocyclic organic compound serving as a critical advanced intermediate in modern chemical synthesis. Its unique fused pyrimidine core structure makes it a valuable building block for developing novel active pharmaceutical ingredients (APIs) and functional materials. This product is essential for research and development laboratories, pharmaceutical companies, and fine chemical manufacturers focused on innovation in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly those targeting specific enzymatic pathways.
• Medicinal Chemistry Research: Used as a core scaffold or building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Development: Serves as an intermediate in the synthesis of novel herbicides, fungicides, or plant growth regulators.
• Material Science: Potential precursor for the synthesis of organic electronic materials, ligands for metal-organic frameworks (MOFs), or specialty polymers.
• Academic & Industrial R&D: Employed in universities and corporate R&D centers for fundamental research in heterocyclic chemistry and reaction methodology development.

Basic Information

Product Name	2-Hydroxy-3-Phenyl-4H-Pyrimido[1,2-A]Pyrimidin-4-One
CAS No.	1306739-05-8
Molecular Formula	C₁₄H₁₀N₂O₂
Molecular Weight	238.24 g/mol
Synonyms	3-Phenyl-2-hydroxy-4H-pyrimido[1,2-a]pyrimidin-4-one; 2-Hydroxy-3-phenylpyrimido[1,2-a]pyrimidin-4-one; 4H-Pyrimido[1,2-a]pyrimidin-4-one, 2-hydroxy-3-phenyl-; Pyrimido[1,2-a]pyrimidin-4-one, 2-hydroxy-3-phenyl-; 1306739-05-8; 2-Hydroxy-3-phenyl-4H-pyrimido[1,2-a]pyrimidin-4-one
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-3-Phenyl-4H-Pyrimido[1,2-A]Pyrimidin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Assay	≥ 95.0% (by titration)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.