Description

4-{[(Dimethylamino)Methyl]Amino}-7-Methylpyrazolo-[5,1-C][1,2,4]Triazine-3-Carbonitrile is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the research and development of novel therapeutic agents, particularly in oncology and targeted drug discovery. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in synthesizing innovative active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates, especially kinase inhibitors.
• Oncology Research: Used in the development of targeted cancer therapies due to its specific molecular scaffold that can interact with biological targets.
• Chemical Biology: Serves as a probe or precursor in studying enzyme function and signal transduction pathways.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of lead compounds.
• Preclinical Development: Used to produce materials for toxicology studies and formulation development of new chemical entities (NCEs).
• Custom Synthesis: A starting material for the contract manufacturing of specialized, high-value compounds for clinical trials.

Basic Information

Product Name	4-{[(Dimethylamino)Methyl]Amino}-7-Methylpyrazolo-[5,1-C][1,2,4]Triazine-3-Carbonitrile
CAS No.	1306738-66-8
Molecular Formula	C11H14N8
Molecular Weight	258.28 g/mol
Synonyms	7-Methyl-4-[[(dimethylamino)methyl]amino]pyrazolo[5,1-c][1,2,4]triazine-3-carbonitrile; 4-((Dimethylaminomethyl)amino)-7-methylpyrazolo[5,1-c][1,2,4]triazine-3-carbonitrile; Pyrazolo[5,1-c][1,2,4]triazine-3-carbonitrile, 4-[[(dimethylamino)methyl]amino]-7-methyl-; CAS 1306738-66-8
EINECS	Contact for details

Quality Control

Our 4-{[(Dimethylamino)Methyl]Amino}-7-Methylpyrazolo-[5,1-C][1,2,4]Triazine-3-Carbonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.