Description

tert-Butyl 4-(2-Hydrazinopyrimidin-4-Yl)-Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a piperazine core functionalized with a hydrazinopyrimidine moiety and a tert-butoxycarbonyl (Boc) protecting group. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel drug candidates. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing therapeutics in areas such as oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex small-molecule active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Kinase Inhibitor Development: The pyrimidine-hydrazine structure makes it valuable for creating potential kinase inhibitors for cancer therapy.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.
• Chemical Biology Probes: Can be utilized to develop molecular probes for studying biological pathways and target validation.

Basic Information

Item	Details
Product Name	tert-Butyl 4-(2-Hydrazinopyrimidin-4-Yl)-Piperazine-1-Carboxylate
CAS No.	1306738-63-5
Molecular Formula	C13H21N5O2
Molecular Weight	279.34 g/mol
Synonyms	1-Boc-4-(2-hydrazinyl-4-pyrimidinyl)piperazine; 4-(2-Hydrazinopyrimidin-4-yl)-1-piperazinecarboxylic acid tert-butyl ester; tert-Butyl 4-(2-hydrazinyl-4-pyrimidinyl)-1-piperazinecarboxylate; 1-(tert-Butoxycarbonyl)-4-(2-hydrazinopyrimidin-4-yl)piperazine; BOC-4-(2-Hydrazinopyrimidin-4-yl)piperazine; 1306738-63-5
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 4-(2-Hydrazinopyrimidin-4-Yl)-Piperazine-1-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere to prevent degradation. For long-term storage, consider storing under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.