Description

(S)-3-(9H-Fluoren-9-Ylmethoxycarbonylamino)-Pentanoic Acid is a high-purity, non-natural amino acid derivative protected with the Fmoc (9-fluorenylmethoxycarbonyl) group. This compound matters as a critical chiral building block for the solid-phase synthesis of peptides and peptidomimetics, enabling the precise construction of complex biomolecules. It is essential for researchers and manufacturers in pharmaceutical development, biotechnology, and advanced materials science who require high-fidelity intermediates for drug discovery and proteomics research.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected amino acid derivative for the automated, sequential assembly of custom peptides.
• Pharmaceutical Intermediate: Used in the research and development of novel therapeutic peptides, hormones, and enzyme inhibitors.
• Bioconjugation & Labeling: Serves as a versatile linker or spacer molecule for attaching functional groups, fluorophores, or other moieties to peptides.
• Peptidomimetic Design: A crucial component for creating modified peptide analogs with enhanced stability, bioavailability, or biological activity.
• Academic & Industrial Research: Employed in biochemistry and molecular biology labs for studying protein-protein interactions and signal transduction pathways.
• Combinatorial Chemistry Libraries: Used to generate diverse arrays of compounds for high-throughput screening in drug discovery campaigns.

Basic Information

Product Name	(S)-3-(9H-Fluoren-9-Ylmethoxycarbonylamino)-Pentanoic Acid
CAS No.	1303993-81-8
Molecular Formula	C24H27NO4
Molecular Weight	393.48 g/mol
Synonyms	Fmoc-β-homoLeu-OH; Fmoc-DL-β-Leucine; (S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)pentanoic acid; Fmoc-β-Leu-OH; N-α-Fmoc-β-homoleucine; N-Fmoc-3-aminopentanoic acid; β-Homoleucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-; Fmoc-β-hLeu-OH
EINECS	Contact for details

Quality Control

Our (S)-3-(9H-Fluoren-9-Ylmethoxycarbonylamino)-Pentanoic Acid is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (S-enantiomer)
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.