Description

D-β-Homoglutamine-Hcl is a high-purity, non-proteinogenic amino acid derivative with the CAS number 1301706-58-0. This compound is a valuable chiral building block, prized for its role in the synthesis of complex peptides and peptidomimetics where structural modification is required. It is essential for research and development in the pharmaceutical and biotechnology sectors, particularly for medicinal chemistry programs targeting metabolic and neurological pathways.

Application

• Pharmaceutical Intermediates: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs) and therapeutic peptides.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to introduce modified glutamine analogs, altering stability, solubility, or biological activity.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and as a probe for investigating amino acid metabolism and transport mechanisms.
• Proteomics & Diagnostics: Can be utilized in the design and synthesis of specialized reagents and standards for mass spectrometry and diagnostic assays.
• Nutraceutical R&D: Investigated for potential applications in the research of specialized amino acid supplements and metabolic modulators.

Basic Information

Product Name	D-β-Homoglutamine-Hcl
CAS No.	1301706-58-0
Molecular Formula	C6H13N2O3•HCl
Molecular Weight	212.64 g/mol
Synonyms	D-β-Homoglutamine hydrochloride; (R)-2-Amino-4-carbamoylbutanoic acid hydrochloride; D-2-Aminopimelic acid 7-amide hydrochloride; D-2-Amino-4-carbamoylbutyric acid HCl; (R)-2,4-Diamino-4-oxobutanoic acid hydrochloride; D-Homo-Gln-OH•HCl; D-β-HGln•HCl
EINECS	Contact for details

Quality Control

Our D-β-Homoglutamine-Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.