Description

Fmoc-L-Orn(Palm)-Oh is a specialized, high-purity protected amino acid derivative, essential for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring precise control over lipophilicity and side-chain functionality in complex peptide sequences. It is primarily utilized in pharmaceutical R&D for the development of novel therapeutic peptides, as well as in bioconjugation and materials science applications where tailored molecular properties are required.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key building block for the controlled introduction of a palmitoyl-modified ornithine residue, enhancing peptide lipophilicity and membrane permeability.
• Therapeutic Peptide Development: Used in the research and production of peptide-based drugs targeting metabolic disorders, oncology, and infectious diseases.
• Lipopeptide Vaccine Adjuvants: Serves as a precursor in synthesizing lipopeptide components that can stimulate immune responses.
• Bioconjugation and Labeling: Facilitates the site-specific attachment of lipid chains to proteins or other biomolecules for studies on cellular uptake and trafficking.
• Antimicrobial Peptide (AMP) Research: Enables the design and synthesis of novel AMPs with optimized hydrophobic character for improved efficacy.
• Chemical Biology Probes: Employed to create tools for investigating protein-lipid interactions and signal transduction pathways.

Basic Information

Product Name	Fmoc-L-Orn(Palm)-Oh
CAS No.	1301706-41-1
Molecular Formula	C39H58N2O5
Molecular Weight	634.89 g/mol
Synonyms	Fmoc-L-ornithine(palmitoyl)-OH; Nδ-Palmitoyl-Nα-Fmoc-L-ornithine; Fmoc-Orn(Palm)-OH; Nα-(9-Fluorenylmethoxycarbonyl)-Nδ-palmitoyl-L-ornithine; Fmoc-Orn(Palmitoyl)-OH; Fmoc-L-Orn(Palm); (2S)-5-(Hexadecanoylamino)-2-(9H-fluoren-9-ylmethoxycarbonylamino)pentanoic acid
EINECS	Contact for details

Quality Control

Our Fmoc-L-Orn(Palm)-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive research and production applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.