Description

4-Bromo-3-Chloro-5-Fluoroaniline is a high-purity halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecules with specific electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting central nervous system (CNS) disorders and anti-infectives.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a monomer or functionalizing agent for creating specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Intermediate for producing complex azo dyes and high-performance pigments.
• Chemical Research & Development: A versatile reagent for medicinal chemistry, facilitating structure-activity relationship (SAR) studies and library synthesis.
• Cross-Coupling Reactions: Valuable substrate in Buchwald-Hartwig amination and other palladium-catalyzed cross-coupling reactions to form carbon-nitrogen bonds.

Basic Information

Product Name	4-Bromo-3-Chloro-5-Fluoroaniline
CAS No.	1297540-69-2
Molecular Formula	C6H4BrClFN
Molecular Weight	224.46 g/mol
Synonyms	1-Amino-4-bromo-3-chloro-5-fluorobenzene; 4-Bromo-3-chloro-5-fluoro-benzenamine; 3-Chloro-4-bromo-5-fluoroaniline; Benzenamine, 4-bromo-3-chloro-5-fluoro-; 5-Fluoro-3-chloro-4-bromoaniline; Aniline, 4-bromo-3-chloro-5-fluoro-
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Chloro-5-Fluoroaniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in the original packaging or amber glass until use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.