Description

[4-(4-Chloro-Pyrimidin-2-Ylamino)-Cyclohexyl]-Carbamic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for medicinal chemistry research and development, offering a versatile building block for creating novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on oncology, antiviral, and other targeted therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of kinase inhibitors and other targeted small-molecule drugs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies during drug discovery.
• API Synthesis: Serves as a crucial precursor in the multi-step manufacturing process of final active pharmaceutical ingredients.
• Chemical Biology Probes: Employed in the development of probes for studying enzyme function and cellular signaling pathways.
• Custom Synthesis: Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects.

Basic Information

Product Name	[4-(4-Chloro-Pyrimidin-2-Ylamino)-Cyclohexyl]-Carbamic Acid tert-Butyl Ester
CAS No.	1289385-84-7
Molecular Formula	C15H22ClN5O2
Molecular Weight	339.82 g/mol
Synonyms	tert-Butyl N-[4-[(4-chloropyrimidin-2-yl)amino]cyclohexyl]carbamate; 4-(4-Chloro-2-pyrimidinylamino)cyclohexylcarbamic Acid 1,1-Dimethylethyl Ester; 4-[(4-Chloropyrimidin-2-yl)amino]cyclohexyl-carbamic Acid tert-Butyl Ester; BOC-4-(4-Chloro-2-pyrimidinylamino)cyclohexylamine; 1289385-84-7; 4-(4-Chloro-pyrimidin-2-ylamino)-cyclohexylcarbamic Acid tert-Butyl Ester
EINECS	Contact for details

Quality Control

Our [4-(4-Chloro-Pyrimidin-2-Ylamino)-Cyclohexyl]-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.