Description

1-(4-Chloro-6-Methyl-Pyrimidin-2-Yl)-Azetidine-3-Carboxylic Acid is a high-purity, heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecules with targeted biological activity, offering researchers precise control over molecular architecture. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs), agrochemicals, and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor research and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its pyrimidine core for bioactivity.
• Chemical Biology & Proteomics: Serves as a versatile scaffold or linker for creating chemical probes and tools to study biological pathways.
• Material Science: Potential building block for advanced polymers or ligands in catalytic systems due to its functionalized azetidine and carboxylic acid groups.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	1-(4-Chloro-6-Methyl-Pyrimidin-2-Yl)-Azetidine-3-Carboxylic Acid
CAS No.	1289385-54-1
Molecular Formula	C9H10ClN3O2
Molecular Weight	227.65 g/mol
Synonyms	Azetidine-3-carboxylic acid, 1-(4-chloro-6-methyl-2-pyrimidinyl)-; 1-(4-Chloro-6-methylpyrimidin-2-yl)azetidine-3-carboxylic acid; 3-Carboxy-1-(4-chloro-6-methylpyrimidin-2-yl)azetidine; 1289385-54-1; Azetidine-3-carboxylic acid derivative (4-chloro-6-methylpyrimidin-2-yl); (4-Chloro-6-methyl-pyrimidin-2-yl)-azetidine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for fine chemical intermediates. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, residual solvents, and related substances are available upon request. We adhere to a quality management system to support our commitment to supply reliability and product integrity for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.