Description

[2-(4-Chloro-Pyrimidin-2-Ylamino)-Cyclohexyl]-Carbamic Acid tert-Butyl Ester is a sophisticated pharmaceutical intermediate and building block of significant interest in modern organic synthesis. This compound matters for its role as a key precursor in the development of targeted therapeutic agents, particularly kinase inhibitors. Pharmaceutical R&D teams and fine chemical manufacturers need this high-purity intermediate to enable efficient and scalable production of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of kinase inhibitors and other small-molecule drug candidates.
• Chemical Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Serves as a key starting material (KSM) or advanced intermediate in the scale-up and commercial manufacturing of APIs.
• Bioconjugation & Probe Development: Potential utility in creating chemical probes for biochemical and pharmacological studies.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects.

Basic Information

Product Name	[2-(4-Chloro-Pyrimidin-2-Ylamino)-Cyclohexyl]-Carbamic Acid tert-Butyl Ester
CAS No.	1289385-53-0
Molecular Formula	C15H23ClN4O2
Molecular Weight	326.82 g/mol
Synonyms	tert-Butyl N-[2-[(4-chloropyrimidin-2-yl)amino]cyclohexyl]carbamate; 2-(4-Chloro-pyrimidin-2-ylamino)-cyclohexylcarbamic acid tert-butyl ester; BOC-4-Chloro-2-aminopyrimidine-cyclohexylamine; (1R,2R)-rel-2-[[(4-Chloro-2-pyrimidinyl)amino]methyl]cyclohexyl carbamic acid 1,1-dimethylethyl ester (isomer); 1289385-53-0; tert-Butyl (2-((4-chloropyrimidin-2-yl)amino)cyclohexyl)carbamate
EINECS	Contact for details

Quality Control

Our production of [2-(4-Chloro-Pyrimidin-2-Ylamino)-Cyclohexyl]-Carbamic Acid tert-Butyl Ester adheres to stringent quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each shipment, supporting your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.