Description

(2,6-Dichloro-Pyrimidin-4-Ylmethyl)-Isopropyl-Amine is a specialized pyrimidine derivative building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its dichloro and amine functionalities offer versatile points for further chemical modification. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to construct complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its pyrimidine core.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal catalysis and organocatalysts.
• Material Science Research: Acts as a monomer or precursor for functional polymers and advanced organic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	(2,6-Dichloro-Pyrimidin-4-Ylmethyl)-Isopropyl-Amine
CAS No.	1289385-44-9
Molecular Formula	C8H11Cl2N3
Molecular Weight	220.10 g/mol
Synonyms	N-[(2,6-Dichloropyrimidin-4-yl)methyl]propan-2-amine; Isopropyl-(2,6-dichloro-pyrimidin-4-ylmethyl)-amine; 1-[(2,6-Dichloro-4-pyrimidinyl)methyl]-2-propanamine; 2,6-Dichloro-4-[(isopropylamino)methyl]pyrimidine; 4-[(Isopropylamino)methyl]-2,6-dichloropyrimidine; (2,6-Dichloro-4-pyrimidinylmethyl)isopropylamine; N-Isopropyl-N-[(2,6-dichloro-4-pyrimidinyl)methyl]amine
EINECS	Contact for details

Quality Control

Our (2,6-Dichloro-Pyrimidin-4-Ylmethyl)-Isopropyl-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support development and commercial projects requiring compliance with various pharmacopeial or internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.