Description

(6-Chloro-2-Methanesulfinyl-Pyrimidin-4-Yl)-Cyclopropyl-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrimidine core functionalized with a cyclopropylamine group. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of targeted therapies, particularly within oncology and antiviral drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for discovering new therapeutic agents.
• API Development: Serves as a key scaffold in the development of novel Active Pharmaceutical Ingredients, especially in oncology research.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of complex molecules for clinical trials.
• Bioconjugation & Probe Synthesis: Can be utilized for creating chemical probes or conjugates for biochemical and diagnostic applications.

Basic Information

Product Name	(6-Chloro-2-Methanesulfinyl-Pyrimidin-4-Yl)-Cyclopropyl-Amine
CAS No.	1289385-22-3
Molecular Formula	C8H10ClN3OS
Molecular Weight	231.70 g/mol
Synonyms	Cyclopropanamine, 1-(6-chloro-2-(methylsulfinyl)-4-pyrimidinyl)-; 1-(6-Chloro-2-(methylsulfinyl)pyrimidin-4-yl)cyclopropanamine; 4-Pyrimidinamine, 6-chloro-N-cyclopropyl-2-(methylsulfinyl)-; (6-Chloro-2-(methylsulfinyl)pyrimidin-4-yl)cyclopropylamine; 6-Chloro-2-(methylsulfinyl)-N-cyclopropylpyrimidin-4-amine
EINECS	Contact for details

Quality Control

Our production of (6-Chloro-2-Methanesulfinyl-Pyrimidin-4-Yl)-Cyclopropyl-Amine adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, ensuring it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.