Description

2-Cyclopropyl-5,7-Dihydro-Pyrrolo[3,4-D]Pyrimidine-6-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. This compound serves as a key building block in the synthesis of complex molecules, offering significant value in streamlining research and production processes. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing novel therapeutics, particularly in oncology and antiviral research.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs) for targeted therapies.
• Oncology Drug Development: Used in research and production of kinase inhibitors and other small-molecule cancer treatments.
• Antiviral Compound Synthesis: Serves as a precursor in the development of novel antiviral agents.
• Chemical Biology Research: Employed as a probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Process Chemistry & Scale-Up: Used in route scouting and optimization for the commercial-scale manufacturing of complex molecules.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	2-Cyclopropyl-5,7-Dihydro-Pyrrolo[3,4-D]Pyrimidine-6-Carboxylic Acid tert-Butyl Ester
CAS No.	1289267-20-4
Molecular Formula	C14H17N3O2
Molecular Weight	259.31 g/mol
Synonyms	tert-Butyl 2-cyclopropyl-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidine-6-carboxylate; 6H-Pyrrolo[3,4-d]pyrimidine-6-carboxylic acid, 2-cyclopropyl-5,7-dihydro-, 1,1-dimethylethyl ester; 2-Cyclopropyl-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidine-6-carboxylic acid tert-butyl ester; BOC-protected pyrrolopyrimidine intermediate; Cyclopropyl-pyrrolopyrimidine tert-butyl ester
EINECS	Contact for details

Quality Control

Our 2-Cyclopropyl-5,7-Dihydro-Pyrrolo[3,4-D]Pyrimidine-6-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.